Case Abstract
Monday, May 14, 2012 at 06:00AM Paige Mackey
Oklahoma State University, '13
IMMUNOHISTOCHEMICAL EXPRESSION OF C-KIT PROTEIN IN CANINE CUTANEOUS PLASMACYTOMAS
*Paige E. Mackey (1), Catherine G. Lamm (2), and Gregory A. Campbell (3)
1 Department of Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater OK; 2 Veterinary Pathological Sciences, University of Glasgow, Glasgow, UK 3 Oklahoma Animal Disease Diagnostic Laboratory, Oklahoma State University, Stillwater, OK.
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c-KIT is proto-oncogene that encodes a tyrosine kinase receptor, KIT, that is expressed by normal cells as well as various neoplasms in both humans and animals. Most notably, c-KIT expression is used for diagnosis and grading of canine mast cell tumors. In this study, immunohistochemistry was used to determine if c-KIT expression occurs in canine plasmacytomas...