2019 SAVMA Symposium Experience

Victoria Villafane, Ross University 

Amidst the hectic life of a veterinarian student, I hesitated before making the decision to travel mid- semester back to the states for SAVMA symposium. Most schools were on spring break but for Ross students, travel consisted of lugging our laptops, notebooks, and all study materials with us and studying throughout the day any break we got. The question came up more than once, of why we would put ourselves through that just for a convention. Since I have never been before, I did not know the answer until I took the chance and packed my bags, heading off to Athens, Georgia. I felt a mix of nerves, excitement, and stress as I settled in on the plane hoping it was all going to be worth it.

Stepping into symposium, I knew I made the right choice. I looked around at the many vet students from all across the country, glanced at the lengthy list of veterinarian names there to give us lectures and guide us through wet labs and I smiled. This wasn’t something I would ever be able to experience during any other part of vet school. I knew I had the opportunity to network with others in my field, listen to lectures expanding my knowledge on what we learn in school, and to strengthen skills during wet labs.

I took a turn into the big exhibit hall full of vendors, promotors, recruiters and was pleasantly overwhelmed with an influx of information. I stopped at the Hills table and was fascinated as they discussed the release of liquid diets for sick animals. My mind flashed back to countless hours of mashing up food and blending it with water into a soupy consistency and hand feeding sick patients and thought of how helpful and amazing this would be to have in hospitals. They also allowed us to practice placing a nasogastric tube on a model which was really neat as I had never done it before. I continued walking around learning about joint supplements, working with exotics opportunities, veterinarians in the army and about AVMA PLIT. As we stopped at the Zoetis booth, I stood in awe as they had a huge board announcing scholarship recipients and there under the RUSVM column was my name. I had no idea they announced the winners at symposium, so it was incredible and special to have been there when I won the scholarship.

I was also able to attend lectures given by veterinarians and it was an inspiring experience as for the first time in my vet journey, I was able to follow along with cases and examples and actually understand the information coming across. It was very encouraging to see the progress I am making as well as expanding my current knowledge base. One example was an oncology lecture given where the presenter discussed cases on osteosarcoma and hemangiosarcoma. Being able to follow along the cases from presenting complaint to treatments to consequences, it gave me the motivation and encouragement to keep working hard being able to experience how it is paying off. I was able to pull my clinical pathology knowledge out and answer questions about what we would expect to see in patients with these conditions and it was satisfying to feel like I can begin to think and communicate like a veterinarian.

Another day, I attended a dental wet lab. I was interested to learn more about topics that we do not go very in depth in at school, so I chose dentistry, not knowing what I was getting into it. At first, it was extremely intimidating and scary to watch the doctors show us what we have to do. I felt like we were on a construction site instead of in a lab with all of the drilling and hammering. I could never have imagined how hard it actually is pulling teeth, but although it was a challenge and I have never felt my arms so sore, I was still ecstatic that I chose this lab and got to practice extracting a whole set of teeth. It is not something I would have gotten to do at school. Not only did I walk out of that lab with a new appreciation for dentistry, but I definitely increased my muscle mass.

Aside from the wealth of veterinary knowledge I left with, I also learned a very valuable lesson; our education is not limited to the classroom and it’s our responsibility to take advantage of opportunities presented to us. Experiences are just as important as our studies. I am so happy I decided to take the trip to SAVMA symposium and I am grateful for the immense impact it has had on my journey as a DVM candidate.

Research Highlight

Check out this abstract for some cool research Sophie Cressman from Ohio State University! She is in the middle of helping with using a mouse model to try and make pretreatment more effective for adoptive cell transfer therapies useful in human cancer treatment, HIV treatment, and CAR T-cell therapy. Pretty cool, huh?

Adoptive T-cell gene therapy, including Chimeric Antigen Receptor (CAR) T-cell therapy, is a new treatment method being investigated as a potential cure for certain cancers and other previously incurable diseases like HIV/AIDS. The efficacy of the therapy can be significantly improved by preconditioning patients before cell transplantation. During preconditioning, lymphodepletion treatment ablates lymphoid cells to create a favorable “space” for the transferred cells. Current lymphodepleting preconditioning methods, however, rely on high doses of toxic and non-specific chemotherapies which often result in variable therapeutic efficacy of CAR T-cells in patients and cause adverse and sometimes deadly side effects.

The general hypothesis is that CD3e-immunotoxin (CD3e-IT) treatment will work as a viable preconditioning method for T-cell gene therapy by depleting all organs’ T cells prior to adoptive T-cell transplant and promoting the survival then repopulation of transplanted T-cells. CD3e-IT, an anti-CD3e monoclonal antibody conjugated with diphtheria toxin, is a potentially safer and more effective preconditioning regimen for adoptive T-cell therapy. The Kim lab has recently developed a murine version of CD3e-IT using murine CD3e monoclonal antibody with Fc silencing mutations and, in a preliminary study, found that CD3e-IT can specifically and effectively ablate the majority of T-cells in all organs, except CXCR5+ follicular T-helper cells (Tfh). Tfh in germinal centers (GC) are especially important in HIV infection as they remain a reservoir for HIV such that viral infection can persist even after antiretroviral therapy. Tfh are also significant therapeutic targets for follicular lymphomas of GC origin including follicular lymphoma, nodular lymphocyte predominant Hodgkin lymphoma, and angioimmunoblastic T-cell lymphoma. The goal of this study is to enhance the safety and efficacy of adoptive T-cell gene therapy by finding lymphodepletion preconditioning treatment conditions that will safely and effectively ablate all T-cells in the body, including Tfh, to promote the survival and functionality of adoptively transferred T-cells.

Vet Students Impacting Environmental Health

Shannon Rudin, University of Minnesota

During the summer and fall of 2017, I was lucky enough to partake in a research project that assessed forest habitat throughout the state of Idaho. The project was centered out of Lewiston, ID and funded by the Clearwater Basin Collaborative with additional partners, including Idaho Fish and Game, the National Forest Service, and the Rocky Mountain Elk Foundation. The research project aimed to survey vegetation and test nutrition samples taken from the habitat provided in the Clearwater Basin Region in respects to its value to elk populations. My team focused on nutritional availability in a variety of forest types throughout the region, including Subalpine Fir, Western Red Cedar, Douglas Fir and Ponderosa Pine. Research for this project began in 2014 after declining elk populations had been observed for years. As elk populations decline, there is a ripple effect that impacts the environment and other wildlife populations. Considering the quality and nutritional content available in habitats allows land management organizations to make more informed decisions to improve the habitat and therefore encourage population growth. Although my field season with this research project went by far too fast, I appreciate the opportunity to work with such a large collaboration that pulled together efforts to consider the quality of environment to support wildlife populations.

"I can has treat, Mom?!"

Check out Kristin Reichert's (University of Wisconsin) adorable furry friends, Riviera (Rivy for short) and Konza living their best lives!

Casual Saturday at the Dog Park

I can haz treat, mom?

Pure Content post 16-mile hike

My Time in D.C.: A Story about Work-Life Integration

Kassandra Schneider, UC Davis

This past summer I had the privilege of attending the AVMA Convention in Washington, D.C. Eye opening doesn’t even begin to describe it - in addition to opening my eyes to the breadth of veterinary opportunities, I was also empowered to believe that these opportunities are within my reach if I simply choose to pursue them. I left with the motivation - perhaps even a compulsion - to do just that. At the same time, I went on this trip with my boyfriend; it was our first time to D.C. and to the East Coast in general. With so much to explore, we had an amazing time perusing museums, seeing the monuments, trying new foods, and going to comedy clubs and music venues. While I had an amazing time both attending the conference and sightseeing, it wasn’t always easy to balance the two. I’d like to share a few of the realizations I had along the way about work-life integration. These realizations can be applied to conference trips like this one as well as to general day-to-day life. 

1. Planning is just the first step in achieving work-life balance; adjustments will need to be made along the way and should align with goals for the experience and for life as a whole. Before the conference, I tried to plan my day so that I would attend a chunk of lectures, break for lunch with my boyfriend and perhaps go on a museum jaunt, then return to the conference and afterwards have the evening free for more sightseeing. For the most part, my planning worked out well, but some changes occurred while I at the convention. Sometimes I’d find out about an event that I just had to attend. Other times I’d miss a lecture because it took longer to walk back from the National Mall than anticipated, or that red-eye flight plus jet lag required that I rest. These changes mostly balanced themselves out, but I had to keep in check any changes with my original goals in going to D.C.: to nurture both my career and my relationship, to both learn and relax. Somewhere there has to be a limit - I could have easily attended every talk in the conference as they were all fascinating, but in doing so I would have totally ignored my boyfriend. On the flip side, I also could have spent much more time enjoying the amazing city, but it would have been at the cost of missing the incredible opportunity I had to attend the convention.           
2. Though planning and calculated adjustments are important to achieving balance, flexibility and a positive attitude when things go awry are equally important. The one time my boyfriend and I taxied to a tourist destination (since I had more talks I wanted to attend soon after), we ended up in entirely the wrong part of town. (It turns out there are four sets of street corners with the same cross street names in D.C., but that’s a rant for another time.) By the time we realized this, the taxi had driven away, stranding us in what felt like a random, middle-of-nowhere neighborhood. At first I was upset about wasting the cab fare, stressed about getting back in time for the conference, and a bit scared of being in an unfamiliar neighborhood. But throughout my freak-out, my ever-patient boyfriend kept repeating the mantra, “Turn mistakes into miracles,” and we would soon do just that. We discovered an amazing mom-and-pop Salvadorian restaurant that we otherwise never would have found, and my fear of the unfamiliar neighborhood was immediately assuaged by the homestyle service we received. After our delicious meal, we learned that the National Zoo was just a short walk away through a hidden gem of a nature park! On the way back, a kind bus driver even let us on free of charge (shh, don’t tell anybody!). While I was unable to attend the talks I wanted, this day ended up being one of the highlights of my trip. With many Type A personalities in the veterinary field, we often feel the need to have perfect control over all situations, but often the best things in life are unplanned accidents that are embraced with an optimistic, open mind.                      
3. Acknowledge that we aren’t any less for having different aspects of our lives. In a panel I once attended about being a mom in veterinary medicine, I was introduced to the idea that if you embrace motherhood, you need to come to terms with the fact that you will neither be fully successful in being a vet nor in being a mom. During this conference I got a sense of what the tradeoffs between work and personal life feel like. I knew I gave up many networking opportunities, yet I was also aware that I was passing up bonding time with my boyfriend. Despite the understanding I have for the sentiment, I also disagree with it: rather than believing I was not fully successful as a vet or as a partner, I instead felt I was fully successful as a human being. It sounds cheesy, but we aren’t made up of component parts - we’re whole people and our careers and our families are all part of us. Taking time to enjoy myself meant that when I was in lectures, I was fully present and squeezing everything possible out of the experience. Had I spent every moment at the convention, I would have become fatigued and probably wouldn’t have enjoyed the convention as much. In one of the conference talks, a museum curator of the “Outbreak” display discussed how she designed the exhibit with tourists’ “museum fatigue” in mind. Through the way I allocated my time in D.C., I avoided both museum fatigue and “conference fatigue.” There’s no shame in living a balanced lifestyle and we aren’t any less for doing so - instead, it gives us the energy and the passion to excel in all the important areas of our lives. 
4. Reflect on the experience and consider what may be done differently next time, while maintaining the perspective that there’s no single correct path. This conference was just the beginning for me - not the be-all, end-all. Next convention in San Diego I may go with classmates and do more networking. In other situations (perhaps if I bring kids, or have other work responsibilities I must attend to while at the conference), I may spend even less time at the convention. Every outcome is a success as long as it meets my current needs - we need to renounce the idea that there’s only one way to do things because in reality there’s so many paths. We know this inherently when we see our fellow classmates who have all taken different routes to achieve their own version of success. That truth doesn’t stop once you’re in vet school or once you’re out. My time in D.C. was life changing and modifications I make to how I approached the conference this year will not change the fact that my first trip was a complete success, with even its imperfections being a crucial part of the journey. 

I have nothing but good words to say about my trip to D.C. and the lessons I’ve learned will continue to guide me through my career and my life as a whole. I will continue to work towards work-life integration in order to pursue a more enriched and meaningful lifestyle, and I hope you will too!