Creative Corner - Jed Daren, University of Georgia

"Go DAWGS!"

Creative Corner - Lauren Brooke Tata, St. Mathew's University

"Dissappearance" 

"The Wolf"

"Unleashed"

Seed the Greatest

Winner, Creative Corner
Gosia Pajak, University of Illinois

The Parent and the Mishap

Honorable Mention - Life as a Vet Student
Sally Moseley, St. Matthew's University

I have always thought of myself as a good pet owner.

That being said, how many discredited parents have told a similar tale?

How I think most pet owners (and many parents, as well) get into trouble is not by lack of caring but lack of knowing.  I have been a huge advocate for client education before I even knew what client education was; I spoke to youth groups about the importance of realizing the responsibility of taking care of a pet before they got a pet, and I also spoke to them about common dangers  pets may face.

I honestly did not inform them of very much, just some basic ideas.  I mostly wanted to encourage those kids to follow the adage “look before you leap” so that they might get the most out of having a pet. 

Somewhere along the line, I must have forgotten my own advice.  I certainly cared, I just did not know.  And I did not learn until the incident, which may be considered the point at which it was “too late”.

For ten years, I had two beautiful female leopard geckos: Fintsy and Coraco.  When I first set up their tank, overjoyed with the thrill of the exotic experience, I had a stack of books about leopard geckos.  I would have told you that I read every single word.  I would have told you, and I would have believed it myself.

Ten years after first pouring sand into that tank, on a cold morning before the sun cared to join us, I woke up to a gargled shriek.  It was a moment where I had no idea what was happening, but I did know that one of my geckos was in pain.  (Later, my vet would try to comfort me by saying reptiles did not feel pain, but I changed his mind that day.)  I jumped out of bed and lifted up my geckos’ favorite cave to find a strange site. 

Fintsy was not only missing a foot, but she was biting her own leg.  Maybe sometime in my veterinary career I will make up some plausible explanation for her biting her own leg.  I wish I could give an explanation now, but all I can come up with at the moment is that it was in response to Coraco biting off her foot. 

I am not sure how many people know about leopard geckos.  Maybe to some people this incident does not look like my fault.

But I have not exactly given the full story yet.  A couple of years before the incident, Coraco bit off Fintsy’s tail.  Why didn’t I separate them after that?  Two reasons: I had my suspicions that Coraco was partially blind, and leopard gecko tails grow back. 

It was not until years later that the incident occurred, and in a panic of Googling I discovered that you are not supposed to let two female leopard geckos live in the same tank.  They fight.  I thought ten years was a long time to go with one “fight” that might have been a blind gecko’s attempt at catching a cricket.  But then I read that everyone said they had geckos for three years or five years or even ten years before they fought. 

If this had happened to everyone, how did I not discover this before?

Needless to say, I felt extremely foolish. 

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Adipose Derived Adult Mesenchymal Stem Cell Therapy for IBD in an Adult Cat

Winner - Cases and Abstracts
Aki Otomo, St. George’s University

Cheddar is my 10 year-old Domestic Shorthair feline who I adopted in 2004 after he had sustained severe sacro-iliac trauma from being hit by a car at the age of 14 months. He initially presented with a necrotic tail pull injury, which required a short tail amputation with extensive urinary catheterization post-operatively.

By the age of 4 years, Cheddar exhibited numerous neurogenic issues including constipation, megacolon, urine retention from detrusor areflexia and fecal incontinence with pudendal nerve impingement. In 2011 his megacolon had progressed to a point where a subtotal colectomy was necessary. Subsequent sequelae included surgical dehiscience and septic peritonitis. In addition, his bladder atony became so severe he required a permanent low profile cystostomy tube for 14 months. Chiropractic adjustment, low level laser therapy and acupuncture allowed the removal of the cystostomy tube due to increased conscious voiding on Cheddar’s part, however he retains approximately 35mL of urine post-void. He currently suffers from chronic ascending multi-drug resistant urinary tract infections. 

In December 2012, he was diagnosed with Inflammatory Bowel Disease (lymphactyic plasmacytic) with minimal villous lymphangiectasia and chronic mild gastritis. Initial therapy with diet change and Budesonide proved unsuccessful as his cachexia, weight loss and vomiting continued. Further Prednisone therapy resulted in a bladder wall fistula at his previous bladder pexy surgical site. Therefore, systemic immuno-supressants and steroids were ruled out as an ongoing treatment option for his IBD. After consulting with both his Internist Dr. Katie Baxter (BVSc, ACVIM) and Surgeon Dr. Alan Kuzma (DVM, ACVS), in July 2013, we enrolled Cheddar in Vet Stem’s IBD Developmental Program to use adipose derived adult mesenchymal stem cell therapy to potentially treat his IBD.

Background

Stem cell therapy is a fairly new form of treatment for a variety of diseases. Current clinical data has proven stem cell therapy to be effective for treatment of certain cases of equine osteoarthiritis, degenerative joint disease, osteochondrosis dissecans, ligament and tendon injuries, sub-chondral bone cysts, meniscal injuries and fractures (Nixon et al., 2008). In feline and canine patients, it is used most often for osteoarthirits (Black et al., 2007 and Black et al., 2008), orthopedic soft tissue injury, polyarthiritis and fractures. Although the complete understanding of the physiological mechanisms of stem cells have yet to be completely elucidated, stem cells are thought to promote healing and decrease inflammation and modulate inflammatory immune responses (De La Garza Rodea, 2011). They have the ability to modulate and control inflammatory cytokines and target areas of chronic inflammation (Fiorina et al., 2009) where they can potentially ‘re-set’ the inflammatory response through regeneration of normal cells and cell function (Zuk et al., 2002). Therefore, there is wide spread interest in researching stem cells to cure autoimmune diseases and disorders (Zuk et al., 2001). 

Currently, there are various clinical trials being conducted on the use of stem cell therapy in felines with chronic renal disease with one such high profile trial being conducted at the Animal Medical Center in New York.

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